Like other AAS, boldenone is an agonist of the androgen receptor (AR).  The activity of boldenone is mainly anabolic , with a low androgenic potency. Boldenone will increase nitrogen retention, protein synthesis, increases appetite and stimulates the release of erythropoietin in the kidneys.  Boldenone was synthesized in an attempt to create a long-acting injectable metandienone , for androgen deficiency disorders. Boldenone acts similar to metandienone with fewer adverse androgenic effects. [ medical citation needed ] Although commonly compared to nandrolone , boldenone lacks progesterone receptor interaction and associated progestogenic side effects.
But the most similar in its properties to boldenone, as oddly enough, turned out to nandrolone. Despite the dissimilarity of the structure of the molecules of the two drugs, and equipoise, nandrolone, and have approximately the same propensity for aromatization (though, of course, unlike that of nandrolone to estradiol conversion takes place without the participation of the aromatase enzyme). Moreover, the androgen receptor stabilization time of these drugs is approximately the same. Nandrolone and equipoise many experts recommend as interchangeable, and believe not entirely appropriate to their one-time use. In my opinion, this is not entirely justified, and that's why.