Hyposecretion of testosterone

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Both the hypothalamus and the pituitary are involved in complex feedback loops with other glands in the body, sending and receiving hormonal signals to maintain homeostasis. Because of its central role in so many systems, pituitary abnormalities can lead to a variety of disorders. Disorders may lead to either hyposecretion or hypersecretion . Deficient growth hormone, for instance, leads to dwarfism, while excess causes gigantism.

The diagnosis of primary versus secondary hypersecretion of a particular hormone is analogous to that of hyposecretion. The concentrations of the hormone and, if relevant, its tropic hormone are measured in plasma or urine. If both concentrations are elevated, then the hormone in question is being secondarily hy-persecreted. For example, if both TSH and TH are increased in plasma, then the increased TH must be secondary to increased TSH. If the hypersecretion is primary, there will be a decreased concentration of the tropic hormone because of negative feedback by the high concentration of the hormone being hyper-secreted. Again as with hyposecretion, one can get hypersecretion of a hypophysiotropic hormone, leading to secondary hypersecretion of an anterior pituitary hormone, leading to tertiary hypersecretion of the peripheral endocrine gland.

Hypogonadism is a medical term which describes a diminished functional activity of the gonads – the testes and ovaries in males and females, respectively – that may result in diminished sex hormone biosynthesis. In layman's terms, it is sometimes called "interrupted stage 1 puberty". Low androgen (., testosterone) levels are referred to as hypoandrogenism and low estrogen (., estradiol) as hypoestrogenism, and may occur as symptoms of hypogonadism in both sexes, but are generally only diagnosed in males and females respectively. Other hormones produced by the gonads which may be decreased by hypogonadism include progesterone, DHEA, anti-Müllerian hormone, activin, and inhibin. Spermatogenesis and ovulation in males and females, respectively, may be impaired by hypogonadism, which, depending on the degree of severity, may result in partial or complete infertility.

Hyposecretion of testosterone

hyposecretion of testosterone

Hypogonadism is a medical term which describes a diminished functional activity of the gonads – the testes and ovaries in males and females, respectively – that may result in diminished sex hormone biosynthesis. In layman's terms, it is sometimes called "interrupted stage 1 puberty". Low androgen (., testosterone) levels are referred to as hypoandrogenism and low estrogen (., estradiol) as hypoestrogenism, and may occur as symptoms of hypogonadism in both sexes, but are generally only diagnosed in males and females respectively. Other hormones produced by the gonads which may be decreased by hypogonadism include progesterone, DHEA, anti-Müllerian hormone, activin, and inhibin. Spermatogenesis and ovulation in males and females, respectively, may be impaired by hypogonadism, which, depending on the degree of severity, may result in partial or complete infertility.

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