G6PD is a genetic disorder affecting the red blood cells. In the affected person the defect is found in an enzyme called Glucose -6-phosphate dehydogenase. Deficiency of this enzyme causes premature breakdown of red blood cells leading to hemolysis. Hemolytic anemia is the most common problem caused due to G6PD. In hemolytic anemia, red blood cells are destroyed faster than they are produced. In people suffering from G6PD deficiency, hemolytic anemia is often triggered as a result of bacterial infection or viral infection. Certain drugs are also known to cause hemolytic anemia. Antimalarial drugs, antibiotics, etc are the main. Hemolytic anemia can also occur in a person who has eaten Fava beans and who is having G6PD deficiency. There are several reasons for fluctuation of platelet, but before that let me know the full medical history if you are suffering from any illness.
It’s like smoking. If you take identical twins and one smokes but the other doesn’t, the smoker is going to end up with a significantly higher white cell count. In Japan, for example, as smoking rates have steadily dropped, so has the normal white count range, such that about 8% of never smoking men would now be flagged as having abnormally low white counts if you used a cutoff like 4. But, that’s because most people were smoking before, when they set that cutoff. So, maybe 3 would be a better lower limit. The inflammation caused by smoking may actually be one of the reasons cigarettes increase the risk of heart attacks, strokes, and other inflammatory diseases. So, do people who have lower white counts have less heart disease, cancer, and overall mortality? Yes, yes, and yes. People with lower white blood cell counts live longer. “Even within the normal range,” every one point drop may be associated with a 20% drop in the risk of premature death.