It is suggested that bioavailable testosterone represents the fraction of circulating testosterone that readily enters cells and better reflects the bioactivity of testosterone than does the simple measurement of serum total testosterone. Also, varying levels of SHBG can result in inaccurate measurements of bioavailable testosterone. Decreased SHBG levels can be seen in obesity, hypothyroidism , androgen use, and nephritic syndrome (a form of kidney disease ). Increased levels are seen in cirrhosis , hyperthyroidism , and estrogen use. In these situations, measurement of free testosterone may be more useful.
Testosterone is a sex hormone; It is naturally produced in both men and women but is made at a much higher level in men. Low testosterone is not just about libido or becoming stronger and bigger in the gym. While this can be an effect of treatment, the condition known as Low T is much more in-depth. It is what gives a male the secondary sex characteristics of a man. Testosterone – which can profoundly reduce energy levels – is responsible for stimulating muscle growth, achieving normal erectile and cognitive functions, restore energy levels and maintaining normal bone density.
TT may help you but it may have adverse (harmful) results. (See discussion of these side effects below.) The Federal Drug Administration (FDA) has said that testosterone drug labels should state that there is a risk for heart disease and stroke for some men using testosterone products. All men should be checked for heart disease and stroke before, and periodically while on, TT. The AUA however, on careful review of evidence-based peer review literature, has stated that there is no strong evidence that TT either increases or decreases the risk of cardiovascular events.