In patients suffering from chronic renal failure (a condition linked to significantly depleted zinc levels) mega-dosing with 250mg/day of zinc was – as to be expected – able to significantly increase serum zinc, testosterone, and LH levels . Another study consisting of 37 infertile-subjects had the men take an undisclosed amount of zinc for 6-months and noted that the men who had testosterone levels on the lower end (less than 480 ng/dL) noticed significant improvements in testosterone and DHT levels, whereas the men on the higher levels of testosterone (more than 480 ng/dL) noted no increases in testosterone, but still significant increases in DHT levels. On an even more positive note, Nine of the subjects were able to conceive a child during the study period.
Research shows little evidence of abnormal or unhealthy psychological changes in men receiving supervised testosterone therapy to treat their low T, according to a study in the journal Therapeutics and Clinical Risk Management. However, mental and physical risks are involved in self-administration of artificial testosterone. Anyone abusing synthetic testosterone, also known as anabolic steroids, may experience episodes of aggressive or violent behavior, along with physical side effects. Bodybuilders, athletes, or anyone who seeks to build muscle mass or achieve other benefits from artificial testosterone should be aware of these risks.